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The 1:1 Diet Medical Reports

Landmark Research on Diabetes

Recently, the DiRECT study, based upon our products and Plan, has changes the way doctors and dietitians all around the world think about the reversal of diabetes. You can read the full research here.

Huge NHS Pilot Study Based Upon Our Plan

In fact, based upon the incredible results of DiRECT, the NHS and Diabetes UK have commissioned a pilot Type 2 diabetes remission study of 5,000 patients.

2020 DIADEM-1 (*New Release @ 2020 May)

Intensive life-style intervention, including initial weight-loss with TDR, delivered 60% diabetes remission in people with early type 2 diabetes mellitus from the Middle East and North Africa studied in Qatar

  1. Summary : Click here to view report summary
  2. The Lancet : Click here to view report
  3. Study Protocol : Click here to view report
  4. Albawaba Press : Click here to view the Press Release

2020 BMJ (* New Release @ 2020 January)

Total Diet Replacement reduced the use of insulin, improved blood glucose control and improved quality of life in insulin-treated people with type 2 diabetes
Click here to view report

2019 DiRECT (*Release @ 2019 March)

Cambridge Weight Plan 800 kcal/d formula diet: weight changes and change in insulin use in insulin-treated obese people with type 2 diabetes.
1. Summary : Click here to view report summary
2. The Lancet : Click here to view report
3. Diabetic Medicine : Click here to view report
4. Cell Metabolism : Click here to view report
5. Medical Xpress : Click here to view report

2018 DROPLET (*Release @ 2018 November)

Doctor Referral of Overweight People to Low Energy total diet replacement Treatment (DROPLET): pragmatic randomised controlled trial
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2018 BMJ (*Release @ 2018 October)

Doctor Referral of Overweight People to Low Energy total diet replacement Treatment (DROPLET): pragmatic randomised controlled trial
Compared with regular weight loss support from a practice nurse, a programme of weekly behavioural support and total diet replacement providing 810 kcal/day seems to be tolerable, and leads to substantially greater weight loss and greater improvements in the risk of cardiometabolic disease
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2018 PREVIEW Report (*Release @ 2018 August)

Men and women respond differently to rapid weight loss:
Metabolic outcomes of a multi-centre intervention study after a low-energy diet in 2500 overweight, individuals with pre-diabetes (PREVIEW)
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PREIVEW description and quote from Prof. Anthony R. Leeds
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2018 PREVIEW Report (*Release @ 2018 August)

Men and women respond differently to rapid weight loss:
Metabolic outcomes of a multi-centre intervention study after a low-energy diet in 2500 overweight, individuals with pre-diabetes (PREVIEW)
Click here to view report

2018 The 1:1 (CWP) Research Digest V6 (*Release @ 2018 March)

The formula for effective weight loss (version 6)
Safe, effective weight loss and maintenance with sustained health benefits using formula low-calorie and very low-calorie diets. A digest of recent research using Cambridge Weight Plan
Click here to view report

2017 Diabetes Forum Insert (*Release @ 2017)

10% Weight Loss in pre-diabetes
Average 10% weight loss in 4 out of 5 people with pre-diabetes
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2017 Diabetes Forum Insert (*Release @ 2017)

10% Weight Loss in pre-diabetes
Average 10% weight loss in 4 out of 5 people with pre-diabetes
Click here to view report

2017 Diabetes Forum Insert (*Release @ 2017)

10% Weight Loss in pre-diabetes
Average 10% weight loss in 4 out of 5 people with pre-diabetes
Click here to view report

2017 Mirror & BBC News (*Release @ 2017 December)

10% Weight Loss in pre-diabetes
Average 10% weight loss in 4 out of 5 people with pre-diabetes
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I beat type 2 diabetes with 200-calorie drinks
Isobel Murray no longer thinks of herself a diabetic
Click here to view report

 

DiRECT study results are published Click here to view report

2017 AJCN (*New Release @ 2017 August)

Long-term weight-loss maintenance in obese patients with knee osteoarthritis: a randomized trial
A formula low-energy diet (LED) reduces weight effectively in obese patients with knee osteoarthritis, but the role of LED in long-term weight-loss maintenance is unclear.
Click here to view report

2017 Australian Commission on Safety and Quality (*New Release @ 2017 August)

Osteoarthritis of the Knee Clinical Care Standard
Osteoarthritis is not an inevitable part of ageing and is not necessarily progressive. Symptoms can be managed and the level of physical activity improved by modifying risk factors such as exercise weight.
Being overweight doubles a person’s risk of developing knee osteoarthritis, while obesity increases the risk more than fourfold.
Click here to view report

2017 BMJ (*New Release @ 2017 August)

Jebb S et al Doctor Referral of Overweight People to a Low-Energy Treatment (DROPLET) in primary care using total diet replacement products: a protocol for a randomised controlled trial
The aim of the Doctor Referral of Overweight People to a Low-Energy Treatment (DROPLET) study is to determine the clinical effectiveness, feasibility and acceptability of referral to a low-energy total diet replacement programme compared with usual weight management interventions in primary care.
Click here to view report

2017 The 1:1 (CWP) Research Digest V5 (*Release @ 2017 March)

The formula for effective weight loss (version 5)
Safe, effective weight loss and maintenance with sustained health benefits using formula low-calorie and very low-calorie diets. A digest of recent research using Cambridge Weight Plan
Click here to view report

2016 The 1:1 (CWP) Research Digest V4

The formula for effective weight loss (version 4)
Safe, effective weight loss and maintenance with sustained health benefits using formula low-calorie and very low-calorie diets. A digest of recent research using Cambridge Weight Plan
Click here to view report

Medical Management

UK National Obesity Forum
Medical Management During Effective Weight Loss
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2016 Diabetic Medicine (*New Release @ 2016 March)

Basic and clinical science posters: new insulins, technology, therapies and treatment
Using a low energy formula diet in obese patients with long-standing type 2 diabetes treated with insulin produces significantly greater weight loss, improvement in glucose control and insulin reductions compared to gold standard clinical care over a 12-week period.
Click here to view report

2015 The 1:1 (CWP) Research Digest V3

The formula for effective weight loss (version 3)
Safe, effective weight loss and maintenance with sustained health benefits using formula low-calorie and very low-calorie diets. A digest of recent research using Cambridge Weight Plan
Click here to view report

2014 Diabetes Asia 2014, 18th October 2014 – Kuala Lumpur, Malaysia

Evidence-based VLCD and LCD therapy for diabetes: cost effective, safe and predictable weight loss and maintenance, with sustained health benefit. – by Professor Anthony R Leeds
Click here to view report

2014 Nutrition Bulletin

Formula food-reducing diets: A new evidence-based addition to the weight management tool box
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2014 European Journal of Preventive Cardiology

A randomised trial comparing weight loss with aerobic exercise in overweight individuals with coronary artery disease: The CUT-IT trial
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2014 Obesity Reviews on behalf of World Obesity

Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons – a scoping review
‘For all obese patients with OA, weight loss should be advocated as a first-line management approach, with a goal of rapid initial weight loss of approximately 10% of body weight.’
Click here to view report

2014 The 1:1 (CWP) Research Digest

The formula for effective weight loss
Safe, effective weight loss and maintenance with sustained health benefits using formula low calorie and very low calorie diets. A digest of recent research using Cambridge Weight Plan

2014 The 1:1 (CWP) UK Medical Brochure

CWP UK Medical Bouchure
Comparing two low-energy diets for the treatment of knee osteoarthritis in obese patients: a pragmatic randomised clinical trial
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2013 Obesity Research

Obesity Journal
Comparison of three different weight maintenance programs on cardiovascular risk, bone and vitamins in sedentary older adults.
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2013 British Journal of General Practice

British Journal of General Practice
Feasibility and indicative results from a 12-month low-energy liquid diet treatment and maintenance programme for severe obesity.
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2013 American Medical Association

Study
Effect of Weight Loss on the Severity of Psoriasis
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Practice Gaps
Gaining insights into the relationship of obesity, weight loss and psoriasis
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Editorial
Psoriasis and the obesity epidemic
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2013 Practice Nursing

More therapy options for obesity needed
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2011 European Journal of Clinical Nutrition

Minerals, trace elements, vitamin D and bone health – Improved nutritional status and bone health after diet-induced weight loss in sedentary osteoarthritis patients: a prospective cohort study
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2011 British Medical Journal (BMJ)

Long term effects of very low energy diet on obstructive sleep apnoea in cohort derived from randomised controlled trial: prospective observational follow-up study
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2011 Clinical Obesity – International Association for the Study of Obesity (IASO)

Does medically induced weight loss improve obstructive sleep apnoea in the obese: review of randomized trial.
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Comparison of a low-energy diet and very low-energy diet in sedentary obese individuals: a pragmatic randomized controlled trial.
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VLED and formula LED in the management of type 2 diabetes: defining the clinical need and research requirements
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Osteoarthritis – a role for weight management in rheumatology practice: an update
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A 60-year-old obese woman with osteoarthritis of the knee: a case-report
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Effect of a very low-energy diet on moderate and severe obstructive sleep apnoea: case reports
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2009 British Medical Journal (BMJ)

Effect of a very low energy diet on moderate and severe obstructive sleep apnoea in obese men: a randomised trial
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Cambridge Weight Matters

2008
1. Bad knees are no excuse for failure to lose weight (2008)
Click here to view report

2009
1. Sleep, sleep apnoea and sleep curtailment (2009)
Click here to view report

2. Research Update – A Cambridge formula-diet weight loss programme is a very effective symptom-reducing treatment in overweight patients with knee osteoarthritis (2009)
Click here to view report

3. A Cambridge very low-calorie diet (VLCD) improved obstructive sleep apnoea in just nine weeks in 26 out of 30 Swedish men
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2010
1. Weight-loss has a significant impact on older, obese people with knee osteoarthritis
Click here to view report

2. New Sleep Apnoea Research Published From Stockholm
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2011
1. Transforming lives with weight maintenance and sustained health benefit.
Click here to view report

2012
1. Cambridge Weight Plan gives improved nutritional status and maintained bone health as well as effective weight loss and weight maintenance in older obese people with knee osteoarthritis
Click here to view report

2013
1. Weight loss and maintenance with formula diet now feasible in primary care
Click here to view report

2. Reduced body weight improves obstructive sleep apnoea
Click here to view report

3. How well did we do in Wales?
Click here to view report

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